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USMLE/1
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Textbook
Introduction
1. Anatomy
1.1 Immune system, blood and lymphoreticular system
1.2 Nervous system and special senses
1.3 Skin and subcutaneous tissue
1.4 Musculoskeletal system
1.5 Anatomy of the cardiovascular system
1.6 Respiratory system
1.7 Respiratory system additional information
1.8 Renal and urinary system
1.9 Renal system additional information
1.10 Gastrointestinal system
1.11 Gastrointestinal system additional information
1.12 Duodenum
1.13 Liver
1.14 Female reproductive system and breast
1.15 Female reproductive system additional information
1.16 Fallopian tubes
1.17 Male reproductive system
1.18 Male reproductive system additional information
1.19 Prostate
1.20 Endocrine system
1.21 Embryology
1.21.1 Gastrointestinal system
1.21.2 Gastrointestinal developmental disorders
1.21.3 Genitourinary system
1.21.4 Nervous system
1.21.5 Respiratory and cardiovascular systems
1.21.6 Pharyngeal arches
1.21.7 Placenta
1.21.8 Umbilical cord and fetal circulation
1.21.9 Additional information
1.22 Additional information
2. Microbiology
3. Physiology
4. Pathology
5. Pharmacology
6. Immunology
7. Biochemistry
8. Cell and molecular biology
9. Biostatistics and epidemiology
10. Genetics
11. Behavioral science
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1.21.9 Additional information
Achievable USMLE/1
1. Anatomy
1.21. Embryology

Additional information

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  1. Box for secondary retroperitoneal organs: These organs are intraperitoneal early in development. Later, their mesenteries are pushed back and fuse with the posterior abdominal wall, so the organs become retroperitoneal. These organs are the pancreas, duodenum, ascending colon, and descending colon.

  2. Embryonic remnants

Embryonic origin Remnant
Foramen ovale Fossa ovalis
Ductus arteriosus Ligamentum arteriosum
Ductus venosus Ligamentum venosum
Umbilical vein Ligamentum teres hepatis
Umbilical arteries Medial umbilical ligament, part of internal iliac and superior vesical arteries.
Mesonephric or Wolffian ducts In males, it becomes the efferent duct system, including the epididymis, vas deferens, and seminal vesicles. In females, it persists as the epoophoron and paroophoron, and as Gartner’s ducts.
Paramesonephric or Mullerian ducts In females, it becomes the fallopian tubes, uterus, cervix, and upper part of the vagina. In males, remnants are seen in the prostatic utricle.
Urachus or allantoic stalk Median umbilical ligament
Notochord Nucleus pulposus
  1. Meconium ileus: This is caused by thick, desiccated meconium that obstructs the ileum. It is seen in newborns with cystic fibrosis.

Meconium ileus presents with bilious vomiting and abdominal distension, with a high risk of perforation and peritonitis.

Prenatal ultrasound shows hyperechoic masses from thick meconium, dilated bowel loops, and non-visualization of the gallbladder.

Postnatal imaging shows dilated bowel loops with or without air-fluid levels (often absent because the meconium is dry), a “soap bubble” or mottled appearance, and in some cases abdominal calcifications. The distal colon shows a microcolon appearance due to disuse.

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