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Introduction
1. Cardiopulmonary system
2. Pulmonary system
3. Neuromuscular system
4. Pediatrics
5. Musculoskeletal system
5.1 Anatomy of musculoskeletal system
5.2 Foundation content of musculoskeletal system
5.3 Anatomy and special tests of upper extremity
5.4 Differential diagnosis with interventions of upper extremity
5.5 Anatomy and special tests of lower extremity
5.6 Differential diagnosis with interventions of lower extremity
5.7 Anatomy and specie tests of spine, pelvis, and temporomandibular joint
5.8 Differential diagnosis with intervention of spine, pelvis, and TMJ
5.9 Other MSK conditions
5.10 Gait
5.11 Prosthetics and orthotics
5.12 Medications, imaging, and fractures
5.13 Surgical protocols
6. Other system
7. Non-systems
Wrapping up
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5.9 Other MSK conditions
Achievable NPTE-PTA
5. Musculoskeletal system

Other MSK conditions

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Osteoarthritis (OA) or degenerative joint disease (DJD)

  • Chronic degenerative joint disease that causes the breakdown of cartilage, the protective tissue that cushions the ends of bones in joints
    • Characterized by articular cartilage with hypertrophy of subchondral bone and joint capsule of weigh-bearing joints
    • Most common form of arthritis
    • Most common joints are cervical spine, lumbar spine, hips, knees, and great toe- weight bearing joints
  • Symptoms
    • Slow, progressive with pain initial episodic and only presents when triggered by specific activity
      • Progressing to chronic with pain present with all weight bearing activities (including ambulation, standing, stair climbing)
    • Swelling in joints
    • Loss of range of motion of joints
    • Bony deformities can occur
  • Diagnosis
    • Clinical presentation
    • X-ray
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
    • Corticosteroids
    • Intra-articular injections into joint space
  • Physical therapy management
    • Joint mobility
    • Joint strengthening
    • Aquatic therapy
    • Aerobic/conditioning activities

Rheumatoid conditions

Rheumatoid arthritis (RA)

  • Chronic autoimmune disease that causes inflammation and damage to the joints due to overproduction of antibodies
    • Etiology is unknown but thought to have genetic links
  • Diseases is characterized by times of exacerbation and remission
  • Most common areas are hands, feet, cervical spine
  • Symptoms (bilateral, symmetrical)
    • Joint pain, especially in the hands, feet, wrists, and knees
    • Swelling and stiffness in the joints
    • Fatigue
    • Fever
    • Deformities in the joints
  • Diagnosis
    • Clinical presentation
    • X-ray imaging
    • Lab values
      • White blood count, erythrocyte sedimentation rate , rheumatoid factor
  • Medical management
    • Antirheumatic medications
    • Immonsupperessive agents
    • Corticosteroids medications
  • Physical therapy management
    • Management of pain and inflammation (during exacerbation phase)
    • Improve joint mobility and mechanics (during remission phase)
    • Resistance training (only during remission phase; contraindicated in exacerbation phase)

Psoriatic arthritis

  • Chronic, inflammatory arthritis that often, but not always, occurs in people with the skin condition psoriasis
    • Autoimmune disorder
  • Typically occurring in axial skeleton and joints of digits
  • Symptoms
    • Joint pain
    • Swelling
    • Stiffness
    • Fatigue
    • Skin psoriasis
    • Changes in fingernails and toenails (discoloration),
    • Inflammation where tendons and ligaments attach to bone
  • Diagnosis
    • Clinical presentation
    • Lab tests only to rule out rheumatoid arthritis
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
    • Antirheumatic medications
    • Biological response modifier medication
  • Physical therapy management
    • Improve joint mobility and mechanics
    • Joint protection strategies
    • Aquatic therapy
    • Aerobic/conditioning activities

Ankylosing spondylitis

  • Chronic inflammatory disease that primarily affects the spine. It causes inflammation of the joints (vertebrae) and ligaments in the spine, leading to stiffness, pain, and eventual fusion of the bones
  • Symptoms
    • Mid and low back pain
    • Morning stiffness of spine
    • Kyphotic deformity of cervical and thoracic spine
    • Decrease lordosis in lumbar spine
    • Degeneration of peripheral and costovertebral joints
  • Diagnosis
    • Clinical presentation
    • Lab tests
      • HLA-B27 antigen
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
    • Corticosteroids medications
    • Cytotoxic drugs
  • Physical therapy management
    • Improve joint mobility and mechanics
    • Joint protection strategies
    • Aquatic therapy
    • Aerobic/conditioning activities
    • Activities to maintain respiratory function
    • Avoidance of high impact sports, resistance activities

Gout

  • Genetic disorder in which uric acid changes into crystal and deposits into peripheral joints
    • Characterized by elevated serum uric acid due to a disorder of purine metabolism
  • Typically occurring in knees and great toes
  • Symptoms
    • Sudden onset of severe, intense pain in one or more joints, typically the big toe.
      • Pain may feel like burning, throbbing, or crushing
    • Significant swelling and redness in the affected joint
    • The joint may feel hot to the touch and tender to the slightest touch
  • Diagnosis
    • Clinical presentation
    • Lab rests
      • Identify uric acid levels
  • Medical management
    • Non-steroidal inflammatory (NSAIDs)
    • Colchicine mediations
    • Corticosteroid medications
    • Allopirinol medications
    • COX-2 inhibitors medications
  • Physical therapy management
    • Prescription of assistive device as appropriate
    • Education on diet restrictions and medication adherence

Tendonosis/tendopathy

  • Tendon dysfunction caused by overuse or repetitive motions that put excessive stress on the tendon
    • Can also be caused by sudden trauma or age-related degeneration
  • Symptoms
    • Pain typically located over the affected tendon, often worse with activity.
    • Swelling present around the tendon.
    • Stiffness at the affected joint.
    • Weakness in joint
  • Diagnosis
    • Clinical presentation
      • Special tests specific to joint
    • MRI
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
    • Corticosteroids medications
  • Physical management
    • Flexibility; joint mobilization
    • Soft tissue techniques to reduce pain and inflammation
    • Progressive resistance training
    • Modalities to management pain and inflammation
    • Functional mobility training

Bursitis

  • Inflammation of bursae due to overuse, trauma, gout, or infection
  • Symptoms
    • Pain at rest
    • PROM and AROM limed by pain (no capsular pattern)
    • Swelling of the joint area
    • Redness over the inflamed bursa
    • Warmth to the affected area may feel hot to the touch
    • Tenderness over the affected area is pressed
  • Diagnosis
    • Clinical presentation
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
  • Physical therapy management
    • Flexibility; joint mobilization
    • Soft tissue techniques to reduce pain and inflammation
    • Progressive resistance training
    • Modalities to management pain and inflammation
    • Functional mobility training

Myofascial pain syndrome

  • Chronic pain condition that affects muscles and the tissue that surrounds them. Characterized by trigger points in muscles that cause pain when pressed
    • Can be caused by sudden overload overstretching and increased repetition
    • Types of trigger points
      • Active trigger points are tender to palpation and can cause referred pain
      • Latent trigger points are taut bands that can be transitioned to active trigger points
  • Symptoms
    • Deep, aching, or throbbing pain that can be localized or widespread.
    • Tender knots in the muscles that cause pain when pressed.
    • Pain that radiates to other areas of the body, such as from the neck to the head or shoulder.
    • Headaches
    • Sleep disturbances
    • Postural changes
  • Diagnosis * Clinical presentation
  • Medical management
    • Dry needling
    • Corticosteroid injections
    • Analgesic injections
  • Physical therapy management
    • Soft tissue techniques to reduce pain and inflammation
    • Progressive resistance training
    • Modalities to management pain and inflammation
    • Functional mobility training
    • Dry needling

Complex regional pain syndrome (CRPS)

  • Chronic pain condition characterized by persistent, severe pain; presentation of symptoms are disproportionate to the initial injury
    • Results in dysfunction of sympathetic nervous system
    • Can be caused by trauma or have unknown etiology
    • Types of complex pain syndrome
      • CRPS I- tissue injury with no nerve involvement
      • CRPs II- tissue injury with known nerve involvement
  • Symptoms
    • Intense, burning, or throbbing pain that is disproportionate to the initial injury
    • Pain that worsens with movement or touch
    • Pain that may spread to other areas of the body
    • Allodynia (pain from normally non-painful stimuli, such as light touch or temperature changes)
    • Hyperalgesia (increased sensitivity to pain)
    • Numbness, tingling, or prickling sensation
    • Changes in skin color, temperature, or sweating
    • Swelling
    • Joint stiffness
  • Diagnosis
    • Clinical presentation
  • Medical management
    • Sympathetic nerve block
    • Spinal cord stimulation
    • Intrathecal drug pumps
    • Antiseziure medications
    • Antidepressants
    • Corticosteroids medications
    • Opioids medications
  • Physical therapy management
    • Patient education on diagnosis and prevention of exacerbating activities
    • Desensitization activities for return to normal function
    • Modalities for pain relief

Muscle strains

  • Injury to the muscle or tendon, the fibrous tissue that connects muscles to bones causing an inflammatory response
    • Typically due to overuse or overstretching caused by forceful movement
  • Symptoms
    • Sudden, sharp, or throbbing pain that worsens with movement
    • Inflammation and fluid buildup in the affected area
    • Discoloration of the skin due to blood vessel damage
    • Difficulty or inability to use the injured muscle
    • Restricted movement in the affected area
    • Feeling tight or sore when the muscle is stretched or contracted
    • Involuntary muscle contractions that can cause sudden pain
    • Pain when the injured muscle is touched or pressed
  • Diagnosis
    • Clinical presentation
    • MRI possibly
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
  • Physical therapy management
    • Soft tissue techniques to reduce pain and inflammation
    • Progressive resistance training
    • Modalities to management pain and inflammation
    • Functional mobility training

Myositis ossificans

  • Abnormal calcification within muscle belly
    • Can be caused by direct trauma- hematoma causes calcification
    • Frequently located in quadriceps or biceps
  • Symptoms
    • Persistent, localized pain that worsens with activity
    • A firm, palpable lump or mass in the injured muscle
    • Limited range of motion
    • Warmth
    • Redness
  • Diagnosis
    • Clinical presentation
    • X-ray imaging
    • CT scan
    • MRI
  • Medical management
    • Acetaminophen or non-steroidal inflammatory (NSAIDs)
  • Physical therapy management
    • Soft tissue techniques to reduce pain and inflammation
    • Progressive resistance training
    • Modalities to management pain and inflammation
    • Functional mobility training

Paget’s disease

  • Chronic bone disorder characterized by abnormal bone remodeling
    • May be linked to viral infections
  • Symptoms
    • Deep, aching pain in the affected bones, often worse at night or with activity.
    • Bowing of the legs or arms
    • Enlargement of the skull or jaw
    • Thickening of the bones in the spine or pelvis
    • Numbness, tingling, or weakness in the arms or legs
    • Headaches
    • Hearing loss
  • Diagnosis
    • Clinical presentation
    • X-ray
    • Lab tests
      • Serum alkaline phosphatase and urinary hydroxypropline
  • Medical management
    • Acetominophen
    • Calcitonin
    • Surgery for bone deformities or joint replacements
  • Physical therapy management
    • Joint protection strategies
    • Improve joint biomechanics
    • Aerobic capacity/conditioning

Osteoporosis

  • ​​Bones become brittle and fragile from loss of tissue to metabolic changes resulting in bone mineral density loss
    • Affects women ten times more than men
      • Can be related to menopause (reduction in estrogen)
    • Common sites are thoracic and lumbar spine, proximal humerus, proximal tibia, pelvis, distal radius
  • Symptoms
    • Bone fractures
    • Back pain
    • Loss of height
    • Brittle nails
    • Dental problems
  • Diagnosis
    • Clinical presentation
    • CT scan
    • Dexa scan (bone density scan)
      • +1.0 or higher: Normal bone density
      • -1.0 to -2.5: Osteopenia (low bone mass)
      • -2.5 or lower: Osteoporosis (weak bones)
  • Medical management
    • Calcium supplement
    • Vitamin D supplement
    • Estrogen - hormone replacement therapy
    • Calcitonin supplement
    • Biophosphonates supplement
  • Physical therapy management
    • Joint protection strategies
    • Improve joint biomechanics
    • Aerobic capacity/conditioning

Osteomyelitis

  • Inflammation of bone caused by infection
  • Symptoms
    • Pain and tenderness in the affected bone
    • Swelling, redness, and warmth over the infected area
    • Drainage of pus from a wound or abscess
    • Limited range of motion in the affected joint
    • Fever and chills
    • Fatigue
    • Malaise
    • Loss of appetite
    • Weight loss
  • Diagnosis
    • Clinical presentation
    • Bone biopsy
    • Lab tests
  • Medical management
    • Antibiotics
    • Surgical debridement if necessary
  • Physical therapy management
    • Joint protection strategies
    • Improve joint biomechanics

Somatic dysfunction

Somatic dysfunction is an impaired or altered function of the body’s framework, **including muscles, joints, and fascia. It is commonly associated with pain, restricted movement, and abnormal tissue texture. **

Diagnosed using the TART criteria

  • Tissue texture changes
  • Asymmetry
  • Restriction of motion
  • Tenderness

Below is a description of somatic dysfunction within each segment type:

Cervical somatic dysfunction

  • Location: Affects the neck (C1-C7).
  • Common causes:
    • Poor posture, whiplash, prolonged screen time, stress-related muscle tension.
  • Symptoms:
    • Neck pain, stiffness, headaches, dizziness, reduced range of motion, possible radiating pain to shoulders or arms.
  • Treatment:
    • Soft tissue mobilization, cervical manipulation, stretching, and postural correction exercises.

Thoracic somatic dysfunction

  • Location: Affects the mid-back (T1-T12).
  • Common causes:
    • Poor posture, kyphotic spine patterns, prolonged sitting, rib dysfunction, respiratory issues.
  • Symptoms:
    • Mid-back stiffness, difficulty taking deep breaths, rib pain, referred pain to chest or upper back, limited spinal rotation.
  • Treatment:
    • Thoracic mobilization, rib articulation techniques, breathing exercises, and spinal extension exercises.

Lumbar somatic dysfunction

  • Location: Affects the lower back (L1-L5).
  • Common causes:
    • Heavy lifting, poor body mechanics, prolonged sitting, muscle imbalances, disc pathology.
  • Symptoms:
    • Lower back pain, stiffness, restricted forward bending, muscle spasms, pain radiating to hips or legs, possible sciatic nerve involvement.
  • Treatment:
    • Lumbar manipulation, core strengthening, stretching, and movement retraining.

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