Skin structure, wound healing, and dressings
Foundational skin information
The integumentary system consists of the skin, hair, nails, glands, and sensory receptors. It serves as the first line of defense against injury, infection, and dehydration while regulating temperature and sensation. Below are the layers of skin and their descriptions:
Epidermis (outermost layer)
- Avascular (no blood vessels)
- Composed of keratinized stratified squamous epithelium
- Key cells:
- Keratinocytes - strength and waterproofing (keratin production)
- Melanocytes - pigmentation and ultraviolet light protection
- Langerhans cells - immune defense
- Merkel cells - touch sensation
- The epidermis is organized into several layers, from the deep stratum basale (site of active cell division) to the superficial stratum corneum, a barrier layer of dead, keratinized cells
Dermis (middle layer)
- Vascularized, supplies nutrients to the epidermis
- Contains:
- Blood vessels
- Nerve endings
- Hair follicles
- Sweat and sebaceous glands
- Collagen and elastin fibers (structural support)
Hypodermis (subcutaneous tissue - deepest layer)
- Composed of: fat (adipose tissue), connective tissue
- Function: insulation, energy storage, shock absorption
Related to skin
- Hair - protects against UV, insulates scalp
- Nails - keratinized structures for protection and dexterity
- Sebaceous (oil) glands - secrete sebum (moisturizes and protects skin)
- Sweat glands - regulate temperature and remove waste
- Eccrine glands - watery sweat, found everywhere
Wound healing phases
Inflammatory phase
- Initiated immediately and lasts 3-4 days
- Marked by hemostasis (stopping bleeding) and phagocytosis (removal of debris and pathogens)
Proliferative phase
- Lasts until day 21 post-injury
- Collagen formation: A whitish protein substance that adds to the tensile strength of the wound
- Eschar formation may occur
Maturation phase
- Begins at day 21 and lasts up to 1-2 years
- Leads to scar formation
Types of healing
Primary intention (first intention)
- Tissue surfaces are closed with minimal tissue loss
- Example: Surgical incision
Secondary intention
- Extensive tissue loss prevents edges from being approximated
- Example: Pressure ulcer
- Longer repair time, increased scarring, and higher infection risk
Tertiary intention healing (delayed closure)
- Wound is left open for a period before closure
- Example: Abdominal wound left open for drainage before later closure
Classification of wound drainage
- Serous - Clear to brownish fluid from the serum portion of blood
- Sanguineous - Bright red, bloody drainage
- Serosanguineous - Pinkish drainage, a mix of blood and serum
- Purulent - Thick, yellow or yellow-green pus, indicating infection
How to measure wounds accurately
Measuring wounds is essential for assessing healing progress and treatment effectiveness. Proper wound measurement includes length, width, depth, and any tunneling or undermining. Below are the tools and steps for how to measure a wound.
Tools needed for wound measurement
- Disposable ruler (centimeters or millimeters)
- Sterile cotton-tipped applicator (for depth)
- Wound probe (for tunneling or undermining)
- Gloves (to maintain infection control)
- Transparent film grid (optional for tracing irregular shapes)
Step-by-step wound measurement
Measuring length and width
- Patient positioning: Ensure the patient is in the same position each time for consistency
- Use a ruler: Place a disposable ruler over the wound
- Length measurement: Measure from the longest point head-to-toe (cephalad to caudal)
- Width measurement: Measure perpendicular to the length, at the widest point from side to side
- Documentation format: Length × Width (e.g., 5.2 cm × 3.4 cm)
Measuring wound depth
- Insert a sterile cotton-tipped applicator into the deepest part of the wound
- Mark the level where it meets the wound edge (this should be perpendicular to the cotton applicator)
- Remove and measure against a ruler
- Example documentation: Depth = 0.8 cm
Measuring wound volume
- Measuring wound volume can be done by multiplying length, width, and depth
- Alternatively, measure the amount of hydrogel required to fill the wound
Steps for measuring tunneling and undermining
- Insert a sterile probe into the suspected tunnel/undermined area
- Measure using a ruler
- Use the clock method to describe location (e.g., “Tunneling at 3 o’clock position, depth 1.5 cm”)
Additional documentation details
- Shape and edges: Irregular, round, oval, jagged
- Tissue type: Granulation, slough, eschar
- Exudate: amount (none, scant, moderate, heavy) and type (serous, purulent, sanguineous)
- Periwound skin: Erythema, edema, maceration, induration
Types of dressing
Gauze dressings
- Names: Sterile gauze, non-sterile gauze, impregnated gauze
- Indications: Used for wounds with moderate to heavy exudate, surgical wounds, and packing deep wounds, and pressure injuries stages III, IV.
- Contraindications: Not ideal for dry wounds (can cause adherence and delay healing)
Transparent film dressings
- Names: Tegaderm, Opsite, Bioclusive
- Indications: Superficial wounds, abrasions, and partial-thickness wounds with minimal exudate; also used for IV sites and pressure injuries stages I, II.
- Contraindications: Should not be used on heavily exudating wounds or infected wounds
Hydrocolloid dressings
- Names: Duoderm, Comfeel, Tegasorb
- Indications: Light to moderate exudating wounds, pressure injuries stage II and shallow stage III, and venous leg ulcers. Helps maintain a moist wound environment.
- Contraindications: Not suitable for infected wounds or wounds with heavy exudate.
Hydrogel dressings
- Names: IntraSite Gel, Aquaform, Vigilon
- Types: Gel, sheet, or beads (for deep wounds)
- Indications: Dry wounds, burns, painful wounds, and wounds with necrotic tissue (autolytic debridement), and pressure injuries stages II, III, IV.
- Contraindications: Should not be used on heavily exudating wounds as it can cause maceration.
Foam dressings
- Names: Allevyn, Mepilex, Lyofoam
- Indications: Moderate to heavily exudating wounds, venous ulcers, pressure ulcers, and diabetic foot ulcers and pressure injuries stages II, III, IV. Provides cushioning.
- Contraindications: Not ideal for dry wounds or wounds with minimal exudate.
Alginate dressings
- Names: Kaltostat, Sorbsan, Algicell
- Indications: Heavy exudating wounds, infected wounds, and wounds with tunneling. Derived from seaweed, absorbs large amounts of fluid, and pressure injuries stages III, IV.
- Contraindications: Not recommended for dry wounds or wounds with minimal exudate.
- Characteristics: When an alginate dressing is removed, it can have a yellowish, tan, or brown color and may have a mild, but unpleasant odor. While the appearance and smell can be alarming, they are often normal and result from the interaction between the seaweed-based dressing and the wound’s exudate.
Collagen dressings
- Names: Promogran, Fibracol, Biostep
- Indications: Chronic non-healing wounds, pressure ulcers, wounds with granulation tissue, and pressure injuries stages II, III, IV.
- Encourages new tissue growth.
- Contraindications: Not for dry wounds or wounds with eschar. Avoid in patients with collagen allergies.
Antimicrobial dressings
- Names: Silvercel, Acticoat, Iodosorb
- Indications: Infected wounds, burns, surgical wounds at risk of infection, and pressure injuries stages II, III, IV. Contains silver or iodine to reduce bacterial load.
- Contraindications: Avoid in patients allergic to silver or iodine. Not recommended for long-term use due to potential cytotoxicity.
