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Introduction
1. Medications
1.1 Generic names and brand names
1.2 Classification of medications
1.3 Drug interactions and contraindications
1.4 Medications by organ system
1.4.1 Anti-neoplastic drugs
1.4.2 Antimicrobials
1.4.3 Medical terminology
1.4.4 Drugs of the endocrine and reproductive system
1.4.5 Respiratory system
1.4.6 Drugs of the cardiovascular system
1.4.7 Gastrointestinal (digestive) system
1.4.8 Drugs of the nervous system
1.4.9 Drugs of the urinary, integumentary, and musculoskeletal systems
1.5 Drug strengths, dose, and dosage forms
1.6 Routes of administration and special handling of drugs
1.7 Medication side effects, adverse effects and allergies
1.8 Indications of medications and dietary supplements
1.9 Drug stability
1.10 Narrow therapeutic index (NTI) medications
1.11 Pharmaceutical incompatibilities
1.12 Proper storage of medications
1.13 Vaccine types and schedules
2. Patient safety and quality assurance
3. Order entry and processing
4. Federal requirements
Wrapping up
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1.4.3 Medical terminology
Achievable PTCE
1. Medications
1.4. Medications by organ system
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Medical terminology

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Definitions
Hypotension

Low blood pressure

Bradycardia

A decrease in heart rate

Tachycardia

An increase in heart rate

Reflex tachycardia

An increase in heart rate caused by a neural response to hypotension

Edema

Swelling caused by fluid buildup in the body, commonly seen in the feet, ankles, or abdomen

Hyperkalemia

High potassium levels in the blood

Angioedema

Swelling of the deeper layers of the skin and tissues, commonly affecting the face, lips, throat, and feet. It’s often triggered by an allergic reaction.

Benign prostatic hyperplasia

A noncancerous enlargement of the prostate gland

Angina

Chest pain or discomfort caused by insufficient blood supply to the heart

Heart failure

A condition in which the heart can’t pump enough blood to meet the body’s needs

Thrombocytopenia

A condition in which the platelet count decreases

Blood clot

A clump of blood cells and a mesh-like protein called fibrin.

It typically begins when platelets form a plug. The clot then grows as fibrin is deposited, and red blood cells become trapped in the fibrin mesh.

Fibrin is the end product of multi-step clotting pathways, in which chemicals called clotting factors are ultimately converted into fibrin.

Embolism

Blockage of a blood vessel by an embolus (most commonly a dislodged blood clot)

Deep vein thrombosis (DVT)

A condition in which a clot forms in the deep veins, most commonly in the legs. The clot can dislodge and travel to other parts of the body, such as the lungs.

Teratogen

A drug or other substance that can cause birth defects in a fetus

Glaucoma

A disease characterized by increased pressure within the eye

Enterohepatic recycling

The recycling (recirculation) of compounds such as bile acids between the small intestine and the liver

Osteoporosis

A condition caused by loss of bone mineral that weakens bone structure and increases fracture risk

Diabetes mellitus

Commonly called diabetes. A disease characterized by chronically elevated blood glucose levels.

The two main types are type 1 and type 2.

In type 1 diabetes, the pancreas produces little to no insulin, and it often presents in childhood.

Type 2 diabetes is more common in adults and involves relative insulin deficiency and insulin resistance (reduced ability of the body to respond to insulin).

Lactic acidosis

A serious condition in which lactic acid builds up in the body, lowering the body’s pH

Transcription

The process of making messenger RNA (mRNA) from DNA; it’s essential for gene expression

Replication

Copying or reproducing (for example, DNA replication)

Progeny

Offspring

Cushing’s syndrome

A condition characterized by high cortisol levels, leading to weight gain, increased blood glucose and lipids, high blood pressure, and other effects of excess glucocorticoids

Anaerobes

Microorganisms that grow in the absence of oxygen

QTc

A measure of electrical conduction in the heart recorded on an EKG. Certain drugs can prolong the QTc, which can lead to cardiac arrest.

Pseudomembranous colitis

Inflammation of the colon with abdominal pain and diarrhea, caused by overgrowth of Clostridium difficile after prolonged exposure to broad-spectrum antibiotics

Stevens-Johnson syndrome

A life-threatening immune reaction to medications or infections that causes blistering and peeling of the skin and mucous membranes

HIV

Human immunodeficiency virus

HBV

Hepatitis B virus

HSV

Herpes simplex virus

RSV

Respiratory syncytial virus

Neutropenia

Low white blood cell count

Encephalopathy

Brain dysfunction that can cause confusion, memory loss, seizures, and altered consciousness

Metabolic syndrome

A cluster of conditions - such as high blood pressure, abdominal obesity, insulin resistance, and dyslipidemia - that increases the risk of heart disease and stroke

Rhabdomyolysis

Breakdown of muscle tissue that can lead to kidney failure. It may be triggered by extreme heat, intense physical activity, muscle injury, and other causes.

Insomnia

A sleep disorder in which it’s difficult to fall asleep, stay asleep, or get good-quality sleep

Hirsutism

Excessive growth of coarse hair on the face and body in females

Cardiovascular terms

  • Hypotension: low blood pressure
  • Bradycardia: decreased heart rate
  • Tachycardia: increased heart rate
    • Reflex tachycardia: neural response to hypotension
  • Angina: chest pain from low heart blood supply
  • Heart failure: heart can’t pump enough blood

Blood and clotting

  • Thrombocytopenia: low platelet count
  • Blood clot: platelets + fibrin mesh trap red blood cells
    • Fibrin: end product of clotting pathways
  • Embolism: vessel blockage by embolus (often clot)
  • Deep vein thrombosis (DVT): clot in deep leg veins, risk of travel to lungs

Edema and related conditions

  • Edema: swelling from fluid buildup (feet, ankles, abdomen)
  • Angioedema: deep tissue swelling, often allergic, affects face/lips/throat/feet

Electrolyte and metabolic disorders

  • Hyperkalemia: high blood potassium
  • Lactic acidosis: lactic acid buildup, lowers body pH
  • Metabolic syndrome: cluster - increased BP, abdominal obesity, insulin resistance, dyslipidemia

Endocrine and bone disorders

  • Benign prostatic hyperplasia: noncancerous prostate enlargement
  • Osteoporosis: bone mineral loss, weak bones, fracture risk
  • Cushing’s syndrome: high cortisol - weight gain, high glucose/lipids, hypertension

Diabetes

  • Diabetes mellitus: chronic high blood glucose
    • Type 1: little/no insulin, childhood onset
    • Type 2: insulin resistance, adult onset

Drug safety and adverse effects

  • Teratogen: causes birth defects
  • Stevens-Johnson syndrome: severe immune reaction, skin/mucous membrane blistering/peeling
  • Rhabdomyolysis: muscle breakdown, kidney failure risk

Infectious disease terms

  • HIV: human immunodeficiency virus
  • HBV: hepatitis B virus
  • HSV: herpes simplex virus
  • RSV: respiratory syncytial virus
  • Anaerobes: grow without oxygen
  • Pseudomembranous colitis: colon inflammation from C. difficile after antibiotics

Other medical terms

  • Glaucoma: increased eye pressure
  • Enterohepatic recycling: compound recirculation between intestine and liver
  • Insomnia: difficulty falling/staying asleep, poor sleep quality
  • Hirsutism: excess coarse hair in females

Genetics and cell biology

  • Transcription: making mRNA from DNA
  • Replication: copying DNA
  • Progeny: offspring

Hematology and immunology

  • Neutropenia: low white blood cell count

Neurology

  • Encephalopathy: brain dysfunction - confusion, memory loss, seizures, altered consciousness

Cardiac monitoring

  • QTc: EKG measure of heart conduction; prolongation can cause cardiac arrest

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Medical terminology

Definitions
Hypotension

Low blood pressure

Bradycardia

A decrease in heart rate

Tachycardia

An increase in heart rate

Reflex tachycardia

An increase in heart rate caused by a neural response to hypotension

Edema

Swelling caused by fluid buildup in the body, commonly seen in the feet, ankles, or abdomen

Hyperkalemia

High potassium levels in the blood

Angioedema

Swelling of the deeper layers of the skin and tissues, commonly affecting the face, lips, throat, and feet. It’s often triggered by an allergic reaction.

Benign prostatic hyperplasia

A noncancerous enlargement of the prostate gland

Angina

Chest pain or discomfort caused by insufficient blood supply to the heart

Heart failure

A condition in which the heart can’t pump enough blood to meet the body’s needs

Thrombocytopenia

A condition in which the platelet count decreases

Blood clot

A clump of blood cells and a mesh-like protein called fibrin.

It typically begins when platelets form a plug. The clot then grows as fibrin is deposited, and red blood cells become trapped in the fibrin mesh.

Fibrin is the end product of multi-step clotting pathways, in which chemicals called clotting factors are ultimately converted into fibrin.

Embolism

Blockage of a blood vessel by an embolus (most commonly a dislodged blood clot)

Deep vein thrombosis (DVT)

A condition in which a clot forms in the deep veins, most commonly in the legs. The clot can dislodge and travel to other parts of the body, such as the lungs.

Teratogen

A drug or other substance that can cause birth defects in a fetus

Glaucoma

A disease characterized by increased pressure within the eye

Enterohepatic recycling

The recycling (recirculation) of compounds such as bile acids between the small intestine and the liver

Osteoporosis

A condition caused by loss of bone mineral that weakens bone structure and increases fracture risk

Diabetes mellitus

Commonly called diabetes. A disease characterized by chronically elevated blood glucose levels.

The two main types are type 1 and type 2.

In type 1 diabetes, the pancreas produces little to no insulin, and it often presents in childhood.

Type 2 diabetes is more common in adults and involves relative insulin deficiency and insulin resistance (reduced ability of the body to respond to insulin).

Lactic acidosis

A serious condition in which lactic acid builds up in the body, lowering the body’s pH

Transcription

The process of making messenger RNA (mRNA) from DNA; it’s essential for gene expression

Replication

Copying or reproducing (for example, DNA replication)

Progeny

Offspring

Cushing’s syndrome

A condition characterized by high cortisol levels, leading to weight gain, increased blood glucose and lipids, high blood pressure, and other effects of excess glucocorticoids

Anaerobes

Microorganisms that grow in the absence of oxygen

QTc

A measure of electrical conduction in the heart recorded on an EKG. Certain drugs can prolong the QTc, which can lead to cardiac arrest.

Pseudomembranous colitis

Inflammation of the colon with abdominal pain and diarrhea, caused by overgrowth of Clostridium difficile after prolonged exposure to broad-spectrum antibiotics

Stevens-Johnson syndrome

A life-threatening immune reaction to medications or infections that causes blistering and peeling of the skin and mucous membranes

HIV

Human immunodeficiency virus

HBV

Hepatitis B virus

HSV

Herpes simplex virus

RSV

Respiratory syncytial virus

Neutropenia

Low white blood cell count

Encephalopathy

Brain dysfunction that can cause confusion, memory loss, seizures, and altered consciousness

Metabolic syndrome

A cluster of conditions - such as high blood pressure, abdominal obesity, insulin resistance, and dyslipidemia - that increases the risk of heart disease and stroke

Rhabdomyolysis

Breakdown of muscle tissue that can lead to kidney failure. It may be triggered by extreme heat, intense physical activity, muscle injury, and other causes.

Insomnia

A sleep disorder in which it’s difficult to fall asleep, stay asleep, or get good-quality sleep

Hirsutism

Excessive growth of coarse hair on the face and body in females

Key points

Cardiovascular terms

  • Hypotension: low blood pressure
  • Bradycardia: decreased heart rate
  • Tachycardia: increased heart rate
    • Reflex tachycardia: neural response to hypotension
  • Angina: chest pain from low heart blood supply
  • Heart failure: heart can’t pump enough blood

Blood and clotting

  • Thrombocytopenia: low platelet count
  • Blood clot: platelets + fibrin mesh trap red blood cells
    • Fibrin: end product of clotting pathways
  • Embolism: vessel blockage by embolus (often clot)
  • Deep vein thrombosis (DVT): clot in deep leg veins, risk of travel to lungs

Edema and related conditions

  • Edema: swelling from fluid buildup (feet, ankles, abdomen)
  • Angioedema: deep tissue swelling, often allergic, affects face/lips/throat/feet

Electrolyte and metabolic disorders

  • Hyperkalemia: high blood potassium
  • Lactic acidosis: lactic acid buildup, lowers body pH
  • Metabolic syndrome: cluster - increased BP, abdominal obesity, insulin resistance, dyslipidemia

Endocrine and bone disorders

  • Benign prostatic hyperplasia: noncancerous prostate enlargement
  • Osteoporosis: bone mineral loss, weak bones, fracture risk
  • Cushing’s syndrome: high cortisol - weight gain, high glucose/lipids, hypertension

Diabetes

  • Diabetes mellitus: chronic high blood glucose
    • Type 1: little/no insulin, childhood onset
    • Type 2: insulin resistance, adult onset

Drug safety and adverse effects

  • Teratogen: causes birth defects
  • Stevens-Johnson syndrome: severe immune reaction, skin/mucous membrane blistering/peeling
  • Rhabdomyolysis: muscle breakdown, kidney failure risk

Infectious disease terms

  • HIV: human immunodeficiency virus
  • HBV: hepatitis B virus
  • HSV: herpes simplex virus
  • RSV: respiratory syncytial virus
  • Anaerobes: grow without oxygen
  • Pseudomembranous colitis: colon inflammation from C. difficile after antibiotics

Other medical terms

  • Glaucoma: increased eye pressure
  • Enterohepatic recycling: compound recirculation between intestine and liver
  • Insomnia: difficulty falling/staying asleep, poor sleep quality
  • Hirsutism: excess coarse hair in females

Genetics and cell biology

  • Transcription: making mRNA from DNA
  • Replication: copying DNA
  • Progeny: offspring

Hematology and immunology

  • Neutropenia: low white blood cell count

Neurology

  • Encephalopathy: brain dysfunction - confusion, memory loss, seizures, altered consciousness

Cardiac monitoring

  • QTc: EKG measure of heart conduction; prolongation can cause cardiac arrest