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Introduction
1. Cardiopulmonary system
2. Pulmonary system
3. Neuromuscular system
4. Pediatrics
4.1 Pediatrics foundational
4.2 Congenital disorders
4.3 Acquired disorders
5. Musculoskeletal system
6. Other system
7. Non systems
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4.1 Pediatrics foundational
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4. Pediatrics
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Pediatrics foundational

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Developmental milestones

Definitions
Developmental milestones
Skills or behaviors performed by most children at a certain age; used to track growth and development.

The following developmental milestones are organized by the age at which they typically occur:

2 months

  • Holds head up in prone to 45 degrees
  • Does not accept weight on the lower extremities
  • No head control during support sitting

4 months

  • Rolls prone to side, supine to side
  • Head control demonstrated in supported sitting
  • Ulnar-palmar grasp
  • No head lag when pulling up to sit

6 months

  • Rolls supine to prone
  • Independent sitting
  • Prone on extended arms and weight shifting with extended arms

8-9 months

  • Creeping
  • Pull to stand via kneeling with furniture
  • Can stand independently for 1-2 seconds
  • Able to transfer objects between hands
  • Independent with side-sitting

10-15 months

  • Independently walking
  • Creeps up/down steps
  • Transfers floor to standing

20 months

  • Ascends steps with step-to-step pattern while holding unilateral rail or hand
  • Uncoordinated running pattern
  • Able to jump from a 2-inch step independently

24 months

  • Ascends steps with step-to-step pattern independently without holding unilateral rail or hand
  • Uncoordinated running at increased speed

Primitive reflexes

Definitions
Primitive reflexes
Involuntary motor responses to a newborn’s environment that originate in the brainstem and function to aid in survival. Each reflex has a time at which it appears and a time at which it is no longer present (age of integration).

The following are the primitive reflexes, along with the age at which each typically appears and integrates:

Rooting

  • Definition: stroking the cheek to allow for locating the bottle nipple or breast for consuming milk
  • Age: appears at birth, integrates by 3-4 months

Moro

  • Definition: protective reflex activated by the sympathetic nervous system that occurs when a loud noise startles an infant
    • Arms and legs extend with fanned out fingers
    • Head extends
    • Infant cries
    • Infant quickly pulls arms/legs back into midline position
  • Age: appears at birth, integrates by 2-4 months

Palmar grasp

  • Definition: grasping of an object when placed in the palm
  • Age: appears at birth, integrates by 5-6 months

Asymmetrical tonic neck reflex

  • Definition: aids infant in developing muscle tone, hand-eye coordination, and motor skills
    • Infant turns head; face-side arm/leg extends, while scalp-side arm/leg flexes
  • Age: appears at birth, integrates by 6 months

Spinal galant

  • Definition: stroking laterally to the spinal column causes lateral flexing to the ipsilateral side
  • Age: appears at birth, integrates by 3-9 months

Tonic labyrinthine reflex

  • Definition: aids the infant in learning how to control the head and neck
    • Neck flexion causes arms/legs to flex
    • Neck extension causes arms/legs to extend
  • Age: appears in utero, integrates by 3.5 years

Symmetrical tonic neck reflex

  • Definition: aids the infant in learning how to control the upper and lower body independently
    • Infant head moves forward; arms flex and legs extend
    • Infant head moves backward; arms extend and legs flex
  • Age: appears at 6-9 months, integrates by 9-11 months

Landau

  • Definition: aids infant in motor control and coordination
    • Infant held horizontally in the air with head and back extended, forming an arch in the back
  • Age: appears at 4-5 months, integrates by 12 months

Babinski

  • Definition: involuntary movement that occurs when the foot is stroked
    • The lateral edge of the foot is stroked, causing extension and fanning of the toes
  • Age: appears at birth, integrates by 2 years

Flexor withdrawal

  • Definition: protective reflex that occurs when a sharp pressure is applied to the sole or the palm, causing withdrawal of the stimulated extremity
  • Age: appears at birth; remains present throughout life

Crossed extension

  • Definition: protective reflex that occurs when a sharp pressure is applied to the sole or the palm, causing withdrawal of the stimulated extremity and extension of the unaffected limb
  • Age: appears at birth; remains present throughout life

Primary standing

  • Definition: an infant, when placed in a standing position, will support some weight and extend lower extremities
  • Age: appears at birth, integrates by 2 months

Primary walking

  • Definition: a protective reflex that occurs when a sharp pressure is applied to the foot, and the trunk is tilted forward, causing reciprocal stepping
  • Age: appears at birth, integrates by 2 months

Plantar grasp

  • Definition: pressure on the sole or lower foot causes the toes to curl
  • Age: appears at birth, integrates by 9 months

Newborn considerations

The normal gestational period is 40 weeks. Infants born before this time have an increased risk of developing congenital anomalies and developmental delays.

Infants are assessed at birth, minute 1, minute 5, and minute 10 after birth via the APGAR scale. The APGAR scale assesses appearance (color), pulse, grimace (reflex irritability), activity, and respirations. Each is scored with a 0, 1, or 2, with the goal of the score being between 7-10. At every assessment, the expectation is that the score will go up. If scores decline below 7, this indicates the presence of pathology and possible complications.

Examination of the newborn also includes assessment of the musculoskeletal system, range of motion, posture, primitive reflexes as appropriate, and tone. Any abnormalities noted will be the rationale for performing specific outcome measures for assessment.

Outcome measures

Alberta infant motor scale (AIMS)

  • Definition: gross motor skills assessment tool used to evaluate weight-bearing, posture, and antigravity movements in infants
  • Age of use: 0-18 months

Peabody developmental motor scales (PDMS-2)

  • Definition: assesses gross and fine motor development to include spontaneous, elicited reflexes, and automatic reactions used primarily for developmental delay
    • More sensitive to change than the Bayley Scales of Infant Development
  • Age of use: 0-42 months

Gross motor function measure (GMFM-88)

  • Definition: measures gross motor function in the cerebral palsy population
    • Focuses on voluntary movement in five phases — prone and supine, sitting, crawling and kneeling, standing, and walking and jumping
  • Age of use: 0-5 years

Bruininks-Oseretsky test of motor proficiency (BOT-2)

  • Definition: developed to measure gross and fine motor skills for individuals with developmental delay
  • Age of use: 4-21 years

Bayley scales of infant development

  • Definition: developed to measure motor and mental scales for children with developmental delay
    • Assesses 5 domains: cognitive, language, motor, social-emotional, adaptive
  • Age of use: birth to 42 months

Functional independence measure for children (WeeFIM)

  • Definition: assesses function in self-care, mobility, locomotion, and social cognition in children following an acute injury, such as spinal cord injury, traumatic brain injury, or multiple fractures
  • Age of use: 3-8 years

Developmental milestones

  • Skills/behaviors expected at specific ages; track growth and development
  • Key milestones by age:
    • 2 months: holds head up prone, no head control in sitting
    • 4 months: rolls side-to-side, head control in sitting, ulnar-palmar grasp
    • 6 months: rolls supine to prone, independent sitting, prone on extended arms
    • 8-9 months: creeping, pull to stand, stands briefly, transfers objects hand-to-hand
    • 10-15 months: independent walking, creeps stairs, floor to stand transfer
    • 20 months: ascends stairs with help, uncoordinated run, jumps from step
    • 24 months: ascends stairs independently, faster uncoordinated running

Primitive reflexes

  • Involuntary responses from brainstem; aid survival; integrate at specific ages
  • Key reflexes:
    • Rooting: cheek stroke, birth–3/4 months
    • Moro: startle, birth–2/4 months
    • Palmar grasp: object in palm, birth–5/6 months
    • Asymmetrical tonic neck: head turn, birth–6 months
    • Spinal galant: lateral trunk stroke, birth–3/9 months
    • Tonic labyrinth: neck flex/extend, in utero–3.5 years
    • Symmetrical tonic neck: head flex/extend, 6–9 months appears, integrates 9–11 months
    • Landau: horizontal suspension, 4/5–12 months
    • Babinski: foot stroke, birth–2 years
    • Flexor withdrawal & Crossed extension: protective, present for life
    • Primary standing/walking: birth–2 months
    • Plantar grasp: toe curl, birth–9 months

Newborn considerations

  • Normal gestation: 40 weeks; preterm increases risk for anomalies/delays
  • APGAR scale: assesses appearance, pulse, grimace, activity, respirations
    • Scored 0–2 each; total 7–10 is normal
    • Assessed at birth, 1, 5, 10 minutes
  • Newborn exam: musculoskeletal, ROM, posture, primitive reflexes, tone

Outcome measures

  • Albert infant scale: gross motor, weight-bearing/posture, 0–18 months
  • Peabody development motor scale: gross/fine motor, reflexes, 0–42 months
  • GMFM-88: gross motor in cerebral palsy, 0–5 years
  • BOT-2: gross/fine motor, developmental delay, 4–21 years
  • Bayley scales: cognitive, language, motor, social-emotional, adaptive, birth–42 months
  • WeeFIM: self-care, mobility, social cognition, 3–8 years

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Pediatrics foundational

Developmental milestones

Definitions
Developmental milestones
Skills or behaviors performed by most children at a certain age; used to track growth and development.

The following developmental milestones are organized by the age at which they typically occur:

2 months

  • Holds head up in prone to 45 degrees
  • Does not accept weight on the lower extremities
  • No head control during support sitting

4 months

  • Rolls prone to side, supine to side
  • Head control demonstrated in supported sitting
  • Ulnar-palmar grasp
  • No head lag when pulling up to sit

6 months

  • Rolls supine to prone
  • Independent sitting
  • Prone on extended arms and weight shifting with extended arms

8-9 months

  • Creeping
  • Pull to stand via kneeling with furniture
  • Can stand independently for 1-2 seconds
  • Able to transfer objects between hands
  • Independent with side-sitting

10-15 months

  • Independently walking
  • Creeps up/down steps
  • Transfers floor to standing

20 months

  • Ascends steps with step-to-step pattern while holding unilateral rail or hand
  • Uncoordinated running pattern
  • Able to jump from a 2-inch step independently

24 months

  • Ascends steps with step-to-step pattern independently without holding unilateral rail or hand
  • Uncoordinated running at increased speed

Primitive reflexes

Definitions
Primitive reflexes
Involuntary motor responses to a newborn’s environment that originate in the brainstem and function to aid in survival. Each reflex has a time at which it appears and a time at which it is no longer present (age of integration).

The following are the primitive reflexes, along with the age at which each typically appears and integrates:

Rooting

  • Definition: stroking the cheek to allow for locating the bottle nipple or breast for consuming milk
  • Age: appears at birth, integrates by 3-4 months

Moro

  • Definition: protective reflex activated by the sympathetic nervous system that occurs when a loud noise startles an infant
    • Arms and legs extend with fanned out fingers
    • Head extends
    • Infant cries
    • Infant quickly pulls arms/legs back into midline position
  • Age: appears at birth, integrates by 2-4 months

Palmar grasp

  • Definition: grasping of an object when placed in the palm
  • Age: appears at birth, integrates by 5-6 months

Asymmetrical tonic neck reflex

  • Definition: aids infant in developing muscle tone, hand-eye coordination, and motor skills
    • Infant turns head; face-side arm/leg extends, while scalp-side arm/leg flexes
  • Age: appears at birth, integrates by 6 months

Spinal galant

  • Definition: stroking laterally to the spinal column causes lateral flexing to the ipsilateral side
  • Age: appears at birth, integrates by 3-9 months

Tonic labyrinthine reflex

  • Definition: aids the infant in learning how to control the head and neck
    • Neck flexion causes arms/legs to flex
    • Neck extension causes arms/legs to extend
  • Age: appears in utero, integrates by 3.5 years

Symmetrical tonic neck reflex

  • Definition: aids the infant in learning how to control the upper and lower body independently
    • Infant head moves forward; arms flex and legs extend
    • Infant head moves backward; arms extend and legs flex
  • Age: appears at 6-9 months, integrates by 9-11 months

Landau

  • Definition: aids infant in motor control and coordination
    • Infant held horizontally in the air with head and back extended, forming an arch in the back
  • Age: appears at 4-5 months, integrates by 12 months

Babinski

  • Definition: involuntary movement that occurs when the foot is stroked
    • The lateral edge of the foot is stroked, causing extension and fanning of the toes
  • Age: appears at birth, integrates by 2 years

Flexor withdrawal

  • Definition: protective reflex that occurs when a sharp pressure is applied to the sole or the palm, causing withdrawal of the stimulated extremity
  • Age: appears at birth; remains present throughout life

Crossed extension

  • Definition: protective reflex that occurs when a sharp pressure is applied to the sole or the palm, causing withdrawal of the stimulated extremity and extension of the unaffected limb
  • Age: appears at birth; remains present throughout life

Primary standing

  • Definition: an infant, when placed in a standing position, will support some weight and extend lower extremities
  • Age: appears at birth, integrates by 2 months

Primary walking

  • Definition: a protective reflex that occurs when a sharp pressure is applied to the foot, and the trunk is tilted forward, causing reciprocal stepping
  • Age: appears at birth, integrates by 2 months

Plantar grasp

  • Definition: pressure on the sole or lower foot causes the toes to curl
  • Age: appears at birth, integrates by 9 months

Newborn considerations

The normal gestational period is 40 weeks. Infants born before this time have an increased risk of developing congenital anomalies and developmental delays.

Infants are assessed at birth, minute 1, minute 5, and minute 10 after birth via the APGAR scale. The APGAR scale assesses appearance (color), pulse, grimace (reflex irritability), activity, and respirations. Each is scored with a 0, 1, or 2, with the goal of the score being between 7-10. At every assessment, the expectation is that the score will go up. If scores decline below 7, this indicates the presence of pathology and possible complications.

Examination of the newborn also includes assessment of the musculoskeletal system, range of motion, posture, primitive reflexes as appropriate, and tone. Any abnormalities noted will be the rationale for performing specific outcome measures for assessment.

Outcome measures

Alberta infant motor scale (AIMS)

  • Definition: gross motor skills assessment tool used to evaluate weight-bearing, posture, and antigravity movements in infants
  • Age of use: 0-18 months

Peabody developmental motor scales (PDMS-2)

  • Definition: assesses gross and fine motor development to include spontaneous, elicited reflexes, and automatic reactions used primarily for developmental delay
    • More sensitive to change than the Bayley Scales of Infant Development
  • Age of use: 0-42 months

Gross motor function measure (GMFM-88)

  • Definition: measures gross motor function in the cerebral palsy population
    • Focuses on voluntary movement in five phases — prone and supine, sitting, crawling and kneeling, standing, and walking and jumping
  • Age of use: 0-5 years

Bruininks-Oseretsky test of motor proficiency (BOT-2)

  • Definition: developed to measure gross and fine motor skills for individuals with developmental delay
  • Age of use: 4-21 years

Bayley scales of infant development

  • Definition: developed to measure motor and mental scales for children with developmental delay
    • Assesses 5 domains: cognitive, language, motor, social-emotional, adaptive
  • Age of use: birth to 42 months

Functional independence measure for children (WeeFIM)

  • Definition: assesses function in self-care, mobility, locomotion, and social cognition in children following an acute injury, such as spinal cord injury, traumatic brain injury, or multiple fractures
  • Age of use: 3-8 years
Key points

Developmental milestones

  • Skills/behaviors expected at specific ages; track growth and development
  • Key milestones by age:
    • 2 months: holds head up prone, no head control in sitting
    • 4 months: rolls side-to-side, head control in sitting, ulnar-palmar grasp
    • 6 months: rolls supine to prone, independent sitting, prone on extended arms
    • 8-9 months: creeping, pull to stand, stands briefly, transfers objects hand-to-hand
    • 10-15 months: independent walking, creeps stairs, floor to stand transfer
    • 20 months: ascends stairs with help, uncoordinated run, jumps from step
    • 24 months: ascends stairs independently, faster uncoordinated running

Primitive reflexes

  • Involuntary responses from brainstem; aid survival; integrate at specific ages
  • Key reflexes:
    • Rooting: cheek stroke, birth–3/4 months
    • Moro: startle, birth–2/4 months
    • Palmar grasp: object in palm, birth–5/6 months
    • Asymmetrical tonic neck: head turn, birth–6 months
    • Spinal galant: lateral trunk stroke, birth–3/9 months
    • Tonic labyrinth: neck flex/extend, in utero–3.5 years
    • Symmetrical tonic neck: head flex/extend, 6–9 months appears, integrates 9–11 months
    • Landau: horizontal suspension, 4/5–12 months
    • Babinski: foot stroke, birth–2 years
    • Flexor withdrawal & Crossed extension: protective, present for life
    • Primary standing/walking: birth–2 months
    • Plantar grasp: toe curl, birth–9 months

Newborn considerations

  • Normal gestation: 40 weeks; preterm increases risk for anomalies/delays
  • APGAR scale: assesses appearance, pulse, grimace, activity, respirations
    • Scored 0–2 each; total 7–10 is normal
    • Assessed at birth, 1, 5, 10 minutes
  • Newborn exam: musculoskeletal, ROM, posture, primitive reflexes, tone

Outcome measures

  • Albert infant scale: gross motor, weight-bearing/posture, 0–18 months
  • Peabody development motor scale: gross/fine motor, reflexes, 0–42 months
  • GMFM-88: gross motor in cerebral palsy, 0–5 years
  • BOT-2: gross/fine motor, developmental delay, 4–21 years
  • Bayley scales: cognitive, language, motor, social-emotional, adaptive, birth–42 months
  • WeeFIM: self-care, mobility, social cognition, 3–8 years

More from Pediatrics

  • Congenital disorders
  • Acquired disorders