Mechanism of action: works on kidneys to stop the conversion of Angiotensin I to converting to Angiotensin II and causes vasodilation in peripheral vascular system
Mechanism of action: increases the duration of the action potential as well as the effective refractory period for cardiac cells
PT implications: signs of congestive heart failure, including dyspnea, rales/crackles, peripheral edema, jugular venous distention, and exercise intolerance
Observational cardiac topics
Pulse (also known as heart beat or rhythm)
0= absent
1+ = weak/thready
2+= normal
3+= increased
4+= bounding
Pitting edema grading (associated with right sided heart failure):
Grade 1: 0-2 mm indentation and rebounds immediately
Grade 2: 3-4 mm indentation and rebounds within 15 seconds
Grade 3: 5-6 mm indentation and rebounds within 30-60 seconds
Grade 4: 8mm or more indentation and rebounds 60 seconds or longer
Auscultation of heart sounds
Image #7
S1:
Normal heart sound
First heart sound when atrioventricular (mitral and tricuspid) valve close
Heard at the 5th intercostal space at midclavicular line
Signals the beginning of systole
Often referred to as “lub”
S2
Normal heart sound
Second heart sound when semilunar (aortic and pulmonary) valves close
Heart at at the second intercostal space along the right sternal boarder
Signals the beginning of diastole
Often referred to as “dub”
S3
Adventitious heart sound in adults and normal in children
Heard between 4th and 5th ribs on left side of chest
Associated with rapid filling of ventricles during early diastole
Often associated with fluid overload or weakened left ventricle which can be indicative heart failure,myocardial infarction, dilated cardiomyopathy, valvular regurgitation, or constrictive pericarditis
S4
Adventitious heart sound in adults and children
Heard between 4th and 5th ribs on left or right side of chest
Associated with reduced ventricular compliance or increased resistance to ventricular filling
Often associated with left ventricular hypertrophy or left sided heart failure
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