Conventionally, a hormone is identified as a chemical substance released into the bloodstream to influence tissues at a distance in a regulatory manner.
Hormones function as both messengers and regulators and can operate endocrine, paracrine, or autocrine pathways.
While most endocrine hormones are peptides, some are amines (T3, T4, dopamine, norepinephrine, and epinephrine) and others are steroids (cortisol, aldosterone, DHEA, androstenedione, testosterone, estradiol, progesterone, vitamin D).
Similar to neurotransmitters, hormones are chemical messengers that must attach to a receptor to convey their signal. In contrast to neurotransmitters, which are discharged close to their target cells, hormones travel throughout the body via the bloodstream, influencing any cells with the appropriate receptor. Thus, hormones tend to have more widespread effects and work more gradually, often creating longer-lasting impacts than neurotransmitters.
Endocrine gland | Associated hormones | Functions |
Pituitary | Growth hormone, releasing and inhibiting hormones (such as thyroid stimulating hormone) | Regulate growth, regulate hormone release |
Thyroid | Thyroxine, triiodothyronine | Regulate metabolism and appetite |
Pineal | Melatonin | Regulate some biological rhythms such as sleep cycles |
Adrenal | Epinephrine, norepinephrine | Stress response, increase metabolic activities |
Pancreas | Insulin, glucagon | Regulate blood sugar levels |
Ovaries | Estrogen, progesterone | Mediate sexual motivation and behavior, reproduction |
Testes | Androgens, such as testosterone | Mediate sexual motivation and behavior, reproduction |
Effects of the endocrine system on behavior
This field examines the link between behavioral traits and inherited genes.
Genes, temperament, and heredity
Adaptive value of traits and behaviors
Interaction between heredity and environment
Experience and behavior
Regulatory genes and behavior
Epigenetics
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