Memory dysfunction, neural networks and plasticity
Memory dysfunctions
Amnesia: Loss of long-term memory due to disease, physical trauma, or psychological trauma.
- Anterograde amnesia: Inability to form new memories after an injury (often involving hippocampal damage), while older memories usually remain intact.
- Retrograde amnesia: Inability to recall events that occurred before the trauma. It primarily affects episodic memories, but forming new memories is often still possible.
Dementia: A chronic condition that impairs memory recall and other mental functions.
Alzheimer’s disease: A form of dementia marked by brain plaques and severe forgetfulness. It can progress to the loss of basic functions such as walking and eating.
Korsakoff’s syndrome: Memory loss linked to chronic alcohol abuse and a thiamine deficiency. It can cause confusion, lack of coordination, and eye movement problems.
Huntington’s disease: A genetic, incurable condition involving memory loss, dementia, and involuntary limb movements, caused by neuronal degeneration.
Forgetting and interference
Decay: Memory traces become less activated over time, which can make recall fade.
Interference: One memory makes it harder to access another.
Proactive interference: Old information blocks new learning.
Retroactive interference: New information disrupts the recall of older knowledge.
Positive transfer: Existing knowledge helps you learn something new - for example, fluency in one language can support learning another language with similar structures.