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Introduction
1. CARS
2. Psych/soc
2.1 Sensing the environment
2.2 Making sense of the environment
2.2.1 Attention
2.2.2 Cognition, cognitive development and issues
2.2.3 Intelligence/intellectual ability
2.2.4 Consciousness and sleep
2.2.5 Conscious-altering drugs and drug addiction
2.2.6 Memory and processing, sensory and short-term memory
2.2.7 Working and long-term memory, forgetting
2.2.8 Memory dysfunction, neural networks and plasticity
2.2.9 Language
2.3 Responding to the world
2.4 Individual influences on behavior
2.5 Social processes and human behavior
2.6 Attitude and behavior change
2.7 Self-identity
2.8 Psych/soc factors affecting interaction and perception
2.9 Elements of social interaction
2.10 Understanding social structure
2.11 Demographic characteristics and processes
2.12 Social inequality
3. Bio/biochem
4. Chem/phys
Wrapping up
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2.2.8 Memory dysfunction, neural networks and plasticity
Achievable MCAT
2. Psych/soc
2.2. Making sense of the environment

Memory dysfunction, neural networks and plasticity

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Memory dysfunctions

Amnesia: Loss of long-term memory due to disease, physical trauma, or psychological trauma.

  • Anterograde amnesia: Inability to form new memories after an injury (often involving hippocampal damage), while older memories usually remain intact.
  • Retrograde amnesia: Inability to recall events that occurred before the trauma. It primarily affects episodic memories, but forming new memories is often still possible.

Dementia: A chronic condition that impairs memory recall and other mental functions.

Alzheimer’s disease: A form of dementia marked by brain plaques and severe forgetfulness. It can progress to the loss of basic functions such as walking and eating.

Korsakoff’s syndrome: Memory loss linked to chronic alcohol abuse and a thiamine deficiency. It can cause confusion, lack of coordination, and eye movement problems.

Huntington’s disease: A genetic, incurable condition involving memory loss, dementia, and involuntary limb movements, caused by neuronal degeneration.

Forgetting and interference

Decay: Memory traces become less activated over time, which can make recall fade.

Interference: One memory makes it harder to access another.

Proactive interference: Old information blocks new learning.

Retroactive interference: New information disrupts the recall of older knowledge.

Positive transfer: Existing knowledge helps you learn something new - for example, fluency in one language can support learning another language with similar structures.

Memory construction and source monitoring

  • Schemas: Mental frameworks that organize and interpret information. They can speed up understanding, but they can also bias what you notice and remember.
  • Construction and reconstruction: Forming new memories and retrieving older ones can introduce changes over time, which may lead to false memories.
  • Misinformation effect: Inaccuracies that occur when a person’s memory of an event is distorted by misleading information introduced after the event.

Amnesia

  • Loss of long-term memory from trauma or disease
  • Anterograde: can’t form new memories post-injury (hippocampal damage)
  • Retrograde: can’t recall pre-injury events, mainly episodic memories

Dementia and related disorders

  • Chronic impairment of memory and mental functions
  • Alzheimer’s: brain plaques, severe forgetfulness, loss of basic functions
  • Korsakoff’s syndrome: memory loss from alcohol abuse, thiamine deficiency, confusion, coordination issues
  • Huntington’s disease: genetic, incurable, memory loss, dementia, involuntary movements

Forgetting and interference

  • Decay: memory traces weaken over time
  • Interference: memories compete, blocking recall
    • Proactive: old info blocks new learning
    • Retroactive: new info disrupts old recall
  • Positive transfer: prior knowledge aids new learning

Memory construction and source monitoring

  • Schemas: mental frameworks, organize info, can bias memory
  • Construction/reconstruction: memory changes over time, risk of false memories
  • Misinformation effect: post-event misleading info distorts memory

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Memory dysfunction, neural networks and plasticity

Memory dysfunctions

Amnesia: Loss of long-term memory due to disease, physical trauma, or psychological trauma.

  • Anterograde amnesia: Inability to form new memories after an injury (often involving hippocampal damage), while older memories usually remain intact.
  • Retrograde amnesia: Inability to recall events that occurred before the trauma. It primarily affects episodic memories, but forming new memories is often still possible.

Dementia: A chronic condition that impairs memory recall and other mental functions.

Alzheimer’s disease: A form of dementia marked by brain plaques and severe forgetfulness. It can progress to the loss of basic functions such as walking and eating.

Korsakoff’s syndrome: Memory loss linked to chronic alcohol abuse and a thiamine deficiency. It can cause confusion, lack of coordination, and eye movement problems.

Huntington’s disease: A genetic, incurable condition involving memory loss, dementia, and involuntary limb movements, caused by neuronal degeneration.

Forgetting and interference

Decay: Memory traces become less activated over time, which can make recall fade.

Interference: One memory makes it harder to access another.

Proactive interference: Old information blocks new learning.

Retroactive interference: New information disrupts the recall of older knowledge.

Positive transfer: Existing knowledge helps you learn something new - for example, fluency in one language can support learning another language with similar structures.

Memory construction and source monitoring

  • Schemas: Mental frameworks that organize and interpret information. They can speed up understanding, but they can also bias what you notice and remember.
  • Construction and reconstruction: Forming new memories and retrieving older ones can introduce changes over time, which may lead to false memories.
  • Misinformation effect: Inaccuracies that occur when a person’s memory of an event is distorted by misleading information introduced after the event.
Key points

Amnesia

  • Loss of long-term memory from trauma or disease
  • Anterograde: can’t form new memories post-injury (hippocampal damage)
  • Retrograde: can’t recall pre-injury events, mainly episodic memories

Dementia and related disorders

  • Chronic impairment of memory and mental functions
  • Alzheimer’s: brain plaques, severe forgetfulness, loss of basic functions
  • Korsakoff’s syndrome: memory loss from alcohol abuse, thiamine deficiency, confusion, coordination issues
  • Huntington’s disease: genetic, incurable, memory loss, dementia, involuntary movements

Forgetting and interference

  • Decay: memory traces weaken over time
  • Interference: memories compete, blocking recall
    • Proactive: old info blocks new learning
    • Retroactive: new info disrupts old recall
  • Positive transfer: prior knowledge aids new learning

Memory construction and source monitoring

  • Schemas: mental frameworks, organize info, can bias memory
  • Construction/reconstruction: memory changes over time, risk of false memories
  • Misinformation effect: post-event misleading info distorts memory