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Textbook
Introduction
1. Cardiovascular system
2. Pulmonary system
3. Neuromuscular system
4. Pediatrics
5. Musculoskeletal system
6. Other systems
7. Non-systems
Wrapping up
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Introduction
Achievable NPTE-PTA

Introduction

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Welcome to the NPTE Physical Therapist Assistant (PTA) Course! This course is designed to help you prepare for the NPTE-PTA exam, reviewing and sharpening the knowledge you built in your PTA program. Through focused content review and practice questions, you’ll strengthen the foundation you need to pass the exam and apply it in patient care.

Course description

PTA scope of practice: The supervising physical therapist evaluates the patient, sets goals, and establishes (or modifies) the plan of care. The PTA implements that plan, collects data, and recognizes and communicates changes in patient status to the PT - the PTA does not evaluate, set goals, or change the plan of care. Keep this distinction in mind, since the exam returns to it across every system covered in this course.

Course outline

This outline previews what’s covered - each topic is taught in depth in its own chapter later in the course.

Cardiovascular system

  • Cardiac anatomy and physiology
  • Conditions
    • CHF, MI, hypertension, DVT, arterial and venous insufficiency
  • Data collection
    • Vital signs, ECGs, lab values, ankle brachial index
  • Cardiac exercise testing and cardiac rehab

Pulmonary system

  • Anatomy, ventilation, and pulmonary function tests
  • Data collection
    • Auscultation, arterial blood gases, lines and tubes
  • Conditions
    • COPD, asthma, cystic fibrosis, pneumonia
  • Interventions
    • Breathing exercises, airway clearance, postural drainage

Neuromuscular system

  • Nervous system anatomy
    • CNS, spinal cord, PNS, UMN vs LMN, dermatomes and myotomes
  • Pathologies
    • Stroke, TBI, SCI, MS, Parkinson’s, ALS, epilepsy, Guillain-Barré syndrome
  • Interventions
    • Motor learning, PNF, neurorehabilitation approaches
    • Outcome measures, medications
  • Vestibular system
    • BPPV and other peripheral vestibular disorders

Pediatrics

  • Developmental milestones, primitive reflexes, pediatric outcome measures
  • Congenital disorders
    • CP, Down syndrome, Duchenne muscular dystrophy
    • DDH, clubfoot, osteogenesis imperfecta
  • Developmental and acquired disorders
    • Legg-Calve-Perthes, SCFE, Osgood-Schlatter
    • Scoliosis, autism, birth injuries

Musculoskeletal system

  • Anatomy and physiology
    • Bones, joints, muscles, ligaments
    • Planes of motion, ROM norms, joint mechanics, phases of healing
  • Data collection
    • Goniometry, MMT
    • Recognizing special-test findings reported by the PT
  • Conditions and interventions by region
    • Upper extremity, lower extremity, spine, pelvis, and TMJ
    • Osteoarthritis, rheumatoid arthritis, fractures, sprains/strains
  • Gait, prosthetics, and orthotics
  • Medications, imaging, and post-surgical protocols
    • Total hip and knee replacement, ACL reconstruction, spinal surgery

Other systems

  • Integumentary system
    • Staging of pressure injuries
    • Wound healing, dressings, debridement techniques
    • Burns and other common skin conditions
  • Lymphedema
  • Gastrointestinal, reproductive, urinary, and renal systems
  • Endocrine and metabolic systems
  • Cancer and psychological conditions
  • Infectious disease, immune disorders, and hematological disorders

Non-systems

  • Modalities
    • Heat, cold, ultrasound, e-stim, traction
  • Safety and equipment
    • Infection control, emergency response, falls, safe patient handling
    • Assistive devices, wheelchairs, lines and tubes
  • Professional responsibilities
    • Ethics, supervision, delegation, documentation
    • Research and evidence-based practice, the ADA

Where to prioritize: The FSBPT content outline weights these areas roughly as follows (approximate, out of the 140 scored items):

  • Musculoskeletal: 31-40 items (~22-29%)
  • Neuromuscular: 27-35 items (~19-25%)
  • Non-systems (equipment, devices, and technologies; modalities; safety; professional responsibilities; research): 22-32 items (~16-23%)
  • Cardiopulmonary: 20-27 items (~14-19%)
  • Other systems: 11-27 items (~8-19%)
  • Integumentary: 3-8 items (~2-6%)

In this course, cardiopulmonary content is split into the Cardiovascular system and Pulmonary system chapters, and integumentary content is taught in Other systems. Pediatrics is not a category on the exam; its conditions are tested within the body systems above.

Eligibility for the NPTE-PTA exam

To be eligible for the NPTE-PTA exam, you must graduate (or be within 90 days of graduating, if your jurisdiction allows it) from a CAPTE-accredited PTA program, or have education judged substantially equivalent, and meet the eligibility criteria established by the Federation of State Boards of Physical Therapy (FSBPT). Additional requirements may vary by state, so it is important to check with your state board for specific eligibility details.

Exam format

The NPTE-PTA exam consists of 180 multiple-choice questions: 140 are scored, and 40 are unscored pretest questions that FSBPT is trying out for future exams. These questions are designed to assess your knowledge in areas such as patient care, interventions, clinical decision-making, and professional responsibilities covering topics of cardiopulmonary, musculoskeletal, neuromuscular, integumentary, other systems, and non-systems content. The exam includes stand-alone items (some with images or video) along with scenario-based sets of 2-5 questions at the end of each section; the only aid provided at the test center is an erasable note board. The exam is computer-based, and you will have 4 hours to complete it.

The passing score for the PTA NPTE (National Physical Therapy Exam) is 600, on a scale of 200 to 800.

  • The score is scaled, meaning it reflects your performance adjusted for difficulty, not just the number of questions you answered correctly.
  • You do not need a specific percentage of questions correct to pass - the raw score needed to pass can vary slightly with each version of the exam due to differences in difficulty.
  • FSBPT does not publish a percentage-correct target, so focus on mastering the content rather than on a raw-score goal.

Tips for success

Weight your study time by how heavily each area is tested: spend the most time on musculoskeletal and neuromuscular content, then non-systems and cardiopulmonary, with lighter review of other systems and integumentary topics.

PTA scope of practice

  • PT evaluates, sets goals, establishes/modifies plan of care
  • PTA implements plan, collects data, reports status changes to PT
  • PTA never evaluates, sets goals, or changes plan of care

Course and exam outline

  • Seven chapters: cardiovascular, pulmonary, neuromuscular, pediatrics, musculoskeletal, other systems (including integumentary), non-systems (modalities, safety and equipment, professional responsibilities)
  • Pediatrics is not an exam category; its conditions are tested within the body systems
  • Approximate weighting (out of 140 scored items):
    • Musculoskeletal: ~22-29%
    • Neuromuscular: ~19-25%
    • Non-systems: ~16-23%
    • Cardiopulmonary: ~14-19%
    • Other systems: ~8-19%
    • Integumentary: ~2-6%

Eligibility

  • Must graduate (or be within 90 days, if jurisdiction allows) from CAPTE-accredited PTA program, or equivalent
  • Must meet FSBPT criteria; check state board for additional requirements

Exam format & scoring

  • 180 multiple-choice questions total: 140 scored, 40 unscored pretest items
  • Includes stand-alone items (some with images/video) and scenario-based sets (2-5 questions)
  • Erasable note board is only aid allowed; computer-based, 4-hour time limit
  • Passing score: 600 on scaled 200-800 range
    • Score adjusted for difficulty, not raw percentage
    • No published percentage-correct target — focus on content mastery

Study strategy

  • Prioritize musculoskeletal and neuromuscular content first
  • Follow with non-systems and cardiopulmonary
  • Lighter review for other systems and integumentary topics
Next  | 1.1 Physiology of cardiac system
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Introduction

Welcome to the NPTE Physical Therapist Assistant (PTA) Course! This course is designed to help you prepare for the NPTE-PTA exam, reviewing and sharpening the knowledge you built in your PTA program. Through focused content review and practice questions, you’ll strengthen the foundation you need to pass the exam and apply it in patient care.

Course description

PTA scope of practice: The supervising physical therapist evaluates the patient, sets goals, and establishes (or modifies) the plan of care. The PTA implements that plan, collects data, and recognizes and communicates changes in patient status to the PT - the PTA does not evaluate, set goals, or change the plan of care. Keep this distinction in mind, since the exam returns to it across every system covered in this course.

Course outline

This outline previews what’s covered - each topic is taught in depth in its own chapter later in the course.

Cardiovascular system

  • Cardiac anatomy and physiology
  • Conditions
    • CHF, MI, hypertension, DVT, arterial and venous insufficiency
  • Data collection
    • Vital signs, ECGs, lab values, ankle brachial index
  • Cardiac exercise testing and cardiac rehab

Pulmonary system

  • Anatomy, ventilation, and pulmonary function tests
  • Data collection
    • Auscultation, arterial blood gases, lines and tubes
  • Conditions
    • COPD, asthma, cystic fibrosis, pneumonia
  • Interventions
    • Breathing exercises, airway clearance, postural drainage

Neuromuscular system

  • Nervous system anatomy
    • CNS, spinal cord, PNS, UMN vs LMN, dermatomes and myotomes
  • Pathologies
    • Stroke, TBI, SCI, MS, Parkinson’s, ALS, epilepsy, Guillain-Barré syndrome
  • Interventions
    • Motor learning, PNF, neurorehabilitation approaches
    • Outcome measures, medications
  • Vestibular system
    • BPPV and other peripheral vestibular disorders

Pediatrics

  • Developmental milestones, primitive reflexes, pediatric outcome measures
  • Congenital disorders
    • CP, Down syndrome, Duchenne muscular dystrophy
    • DDH, clubfoot, osteogenesis imperfecta
  • Developmental and acquired disorders
    • Legg-Calve-Perthes, SCFE, Osgood-Schlatter
    • Scoliosis, autism, birth injuries

Musculoskeletal system

  • Anatomy and physiology
    • Bones, joints, muscles, ligaments
    • Planes of motion, ROM norms, joint mechanics, phases of healing
  • Data collection
    • Goniometry, MMT
    • Recognizing special-test findings reported by the PT
  • Conditions and interventions by region
    • Upper extremity, lower extremity, spine, pelvis, and TMJ
    • Osteoarthritis, rheumatoid arthritis, fractures, sprains/strains
  • Gait, prosthetics, and orthotics
  • Medications, imaging, and post-surgical protocols
    • Total hip and knee replacement, ACL reconstruction, spinal surgery

Other systems

  • Integumentary system
    • Staging of pressure injuries
    • Wound healing, dressings, debridement techniques
    • Burns and other common skin conditions
  • Lymphedema
  • Gastrointestinal, reproductive, urinary, and renal systems
  • Endocrine and metabolic systems
  • Cancer and psychological conditions
  • Infectious disease, immune disorders, and hematological disorders

Non-systems

  • Modalities
    • Heat, cold, ultrasound, e-stim, traction
  • Safety and equipment
    • Infection control, emergency response, falls, safe patient handling
    • Assistive devices, wheelchairs, lines and tubes
  • Professional responsibilities
    • Ethics, supervision, delegation, documentation
    • Research and evidence-based practice, the ADA

Where to prioritize: The FSBPT content outline weights these areas roughly as follows (approximate, out of the 140 scored items):

  • Musculoskeletal: 31-40 items (~22-29%)
  • Neuromuscular: 27-35 items (~19-25%)
  • Non-systems (equipment, devices, and technologies; modalities; safety; professional responsibilities; research): 22-32 items (~16-23%)
  • Cardiopulmonary: 20-27 items (~14-19%)
  • Other systems: 11-27 items (~8-19%)
  • Integumentary: 3-8 items (~2-6%)

In this course, cardiopulmonary content is split into the Cardiovascular system and Pulmonary system chapters, and integumentary content is taught in Other systems. Pediatrics is not a category on the exam; its conditions are tested within the body systems above.

Eligibility for the NPTE-PTA exam

To be eligible for the NPTE-PTA exam, you must graduate (or be within 90 days of graduating, if your jurisdiction allows it) from a CAPTE-accredited PTA program, or have education judged substantially equivalent, and meet the eligibility criteria established by the Federation of State Boards of Physical Therapy (FSBPT). Additional requirements may vary by state, so it is important to check with your state board for specific eligibility details.

Exam format

The NPTE-PTA exam consists of 180 multiple-choice questions: 140 are scored, and 40 are unscored pretest questions that FSBPT is trying out for future exams. These questions are designed to assess your knowledge in areas such as patient care, interventions, clinical decision-making, and professional responsibilities covering topics of cardiopulmonary, musculoskeletal, neuromuscular, integumentary, other systems, and non-systems content. The exam includes stand-alone items (some with images or video) along with scenario-based sets of 2-5 questions at the end of each section; the only aid provided at the test center is an erasable note board. The exam is computer-based, and you will have 4 hours to complete it.

The passing score for the PTA NPTE (National Physical Therapy Exam) is 600, on a scale of 200 to 800.

  • The score is scaled, meaning it reflects your performance adjusted for difficulty, not just the number of questions you answered correctly.
  • You do not need a specific percentage of questions correct to pass - the raw score needed to pass can vary slightly with each version of the exam due to differences in difficulty.
  • FSBPT does not publish a percentage-correct target, so focus on mastering the content rather than on a raw-score goal.

Tips for success

Weight your study time by how heavily each area is tested: spend the most time on musculoskeletal and neuromuscular content, then non-systems and cardiopulmonary, with lighter review of other systems and integumentary topics.

Key points

PTA scope of practice

  • PT evaluates, sets goals, establishes/modifies plan of care
  • PTA implements plan, collects data, reports status changes to PT
  • PTA never evaluates, sets goals, or changes plan of care

Course and exam outline

  • Seven chapters: cardiovascular, pulmonary, neuromuscular, pediatrics, musculoskeletal, other systems (including integumentary), non-systems (modalities, safety and equipment, professional responsibilities)
  • Pediatrics is not an exam category; its conditions are tested within the body systems
  • Approximate weighting (out of 140 scored items):
    • Musculoskeletal: ~22-29%
    • Neuromuscular: ~19-25%
    • Non-systems: ~16-23%
    • Cardiopulmonary: ~14-19%
    • Other systems: ~8-19%
    • Integumentary: ~2-6%

Eligibility

  • Must graduate (or be within 90 days, if jurisdiction allows) from CAPTE-accredited PTA program, or equivalent
  • Must meet FSBPT criteria; check state board for additional requirements

Exam format & scoring

  • 180 multiple-choice questions total: 140 scored, 40 unscored pretest items
  • Includes stand-alone items (some with images/video) and scenario-based sets (2-5 questions)
  • Erasable note board is only aid allowed; computer-based, 4-hour time limit
  • Passing score: 600 on scaled 200-800 range
    • Score adjusted for difficulty, not raw percentage
    • No published percentage-correct target — focus on content mastery

Study strategy

  • Prioritize musculoskeletal and neuromuscular content first
  • Follow with non-systems and cardiopulmonary
  • Lighter review for other systems and integumentary topics

Related readings

  • Wrapping up