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Introduction
1. Medications
2. Patient safety and quality assurance
3. Order entry and processing
4. Federal requirements
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1.4.5.1 Introduction to the respiratory system and medications
Achievable PTCE
1. Medications
1.4. Medications by organ system
1.4.5. Respiratory system
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Introduction to the respiratory system and medications

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The respiratory system exchanges oxygen (O(_2)) and carbon dioxide (CO(_2)) through two main processes:

  • Inspiration (inhaling), which brings air into the lungs
  • Expiration (exhaling), which moves air out of the lungs

It includes structures in the upper and lower respiratory tracts, such as the nose, trachea, bronchi, and lungs.

Asthma is a common respiratory disease caused by an abnormal allergic response. This response leads to inflammation and narrowing of the airways, which makes breathing more difficult. Several medication classes are used to treat asthma:

  • Some are used as rescue medications for quick relief during an attack
  • Others are used to prevent attacks and reduce their severity over time

Chronic obstructive pulmonary disease (COPD) includes chronic bronchitis and emphysema. These conditions cause long-term breathing problems.

An acute infection of the lung tissues is called pneumonia. Pneumonia is treated with antimicrobials tailored to the causative microorganism.

Table showing common drug classes and examples of the respiratory system

Drug class Generic name Brand name(s) Primary use
Beta 2 agonists Albuterol, salmeterol Ventolin, Serevent Diskus Asthma, COPD
Inhaled Corticosteroids Budesonide, fluticasone Pulmicort Flexhaler, Flovent HFA Asthma, COPD
Anticholinergics or muscarinic antagonists Ipratropium, tiotropium Atrovent, Spiriva Respimat COPD
Leukotriene modifiers Montelukast, zafirlukast Singulair, Accolate Asthma, allergies
Antihistamines Diphenhydramine, cetirizine, loratidine Benadryl, Zyrtec, Claritin Allergies
Antitussives Benzonatate, dextromethorphan Tessalon, Delsym Treatment of cough
Decongestants Phenylephrine, pseudoephedrine Sudafed Treatment of nasal congestion
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