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Introduction
1. Medications
2. Patient safety and quality assurance
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1.4.8.1 Introduction to the nervous system and medications
Achievable PTCE
1. Medications
1.4. Medications by organ system
1.4.8. Drugs of the nervous system
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Introduction to the nervous system and medications

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The nervous system is the body’s main control and communication system. It coordinates muscle movement and speech, supports thinking and emotions, and helps with everyday tasks like planning and learning.

It also helps regulate other organs in two main ways:

  • Through peripheral nerves, which carry signals between the brain/spinal cord and the rest of the body
  • Through hormonal secretion, which influences body functions over longer time periods

The nervous system includes the following structures:

  • Brain
  • Spinal cord
  • Cranial nerves
  • Peripheral nerves

Common nervous system diseases include stroke, epilepsy, Parkinson’s disease, Alzheimer’s disease, and multiple sclerosis.

Tables showing common drug classes and examples of the nervous system

Analgesics

Drug class Generic name Brand name(s) Primary use
Nonsteroidal anti-inflammatory drugs (NSAIDs) Ibuprofen, naproxen, diclofenac Voltaren, Advil, Motrin, Aleve Pain, fever, inflammation
COX 2 inhibitors Celecoxib, rofecoxib Celebrex, Vioxx Arthritis, pain, inflammatory conditions
Narcotic analgesics Morphine, fentanyl, oxycodone, methadone OxyContin, Fentora, Vicodin, Kadian Pain relief, de-addiction therapy
Salicylates Aspirin Bayer Aspirin Pain, fever, inflammation, ischemic heart disease

Antidepressants

Drug class Generic name Brand name(s) Primary use
Selective serotonin reuptake inhibitors (SSRIs) Citalopram, fluoxetine, sertraline Celexa, Prozac, Zoloft Depression, anxiety, eating disorders, obsessive compulsive disorders, PTSD
Serotonin-norepinephrine reuptake inhibitors (SNRIs) Duloxetine, venlafaxine, desvenlafaxine Cymbalta, Effexor, Pristiq Depression, anxiety, eating disorders, obsessive compulsive disorders, PTSD
Tricyclic antidepressants (TCAs) Amitriptyline, doxepin, imipramine Elavil, Tofranil, Sinequan Depression, anxiety, eating disorders, obsessive compulsive disorders, PTSD

Other drug classes of the nervous system

Drug class Generic name Brand name(s) Primary use
Antiepileptics Carbamazepine, gabapentin, phenytoin, valproic acid Tegetrol, Gralise, Dilantin, Depakote Prevention and treatment of epilepsy and seizures
Antipsychotics Haloperidol, loxapine, pimozide Haldol, Adasuve, Orap Treatment of schizophrenia and psychosis
Anxiolytics Buspirone BuSpar, Vanspar Treatment of anxiety, phobias, and panic disorder
Sedative-hypnotics Zolpidem, phenobarbital, alprazolam, diazepam Ambien, Sezaby, Xanax, Valium Treatment of insomnia, to decrease stress and anxiety
Topical anesthetics Lidocaine, bupivacaine, dibucaine, pramoxine Xylocaine, Marcaine, Nupercainal, Pramox To numb skin before local surgery
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